Jaffe-Campanacci syndrome
Last revised by Subhan Iqbal on 27 Feb 2021
Citation, DOI, disclosures and article data
Citation:
Agrawal R, Iqbal S, Thurston M, et al. Jaffe-Campanacci syndrome. Reference article, Radiopaedia.org (Accessed on 19 Apr 2024) https://doi.org/10.53347/rID-1532
rID:
1532
Article created:
2 May 2008,
Rishi Agrawal
Disclosures:
At the time the article was created Rishi Agrawal had no recorded disclosures.
View Rishi Agrawal's current disclosures
Last revised:
27 Feb 2021,
Subhan Iqbal
Disclosures:
At the time the article was last revised Subhan Iqbal had no recorded disclosures.
View Subhan Iqbal's current disclosures
Revisions:
13 times, by
10 contributors -
see full revision history and disclosures
Systems:
Sections:
Tags:
Synonyms:
- Campanacci syndrome
Jaffe-Campanacci syndrome is characterized by:
- multiple non-ossifying fibromas of the long bones and jaw
- café au lait spots
- intellectual disability
- kyphoscoliosis
- hypogonadism or cryptorchidism
- ocular malformations
- cardiovascular malformations
- giant cell granuloma of the jaw
- axillary and inguinal freckling 7
History and etymology
It is named after Mario Campanacci, Italian physician (1932-1999), and Henry Lewis Jaffe, American pathologist (1896-1979) 4-6.
Differential diagnosis
Consider:
References
- 1. Al-Rikabi AC, Ramaswamy JC, Bhat VV. Jaffe-Campanacci syndrome. Saudi Med J. 2005;26 (1): 104-6. Pubmed citation
- 2. Kourelis TV, Manola A. Interesting medical images: the Jaffe-Campanacci syndrome. Conn Med. 2012;76 (5): 279-81. Pubmed citation
- 3. Mankin HJ, Trahan CA, Fondren G et-al. Non-ossifying fibroma, fibrous cortical defect and Jaffe-Campanacci syndrome: a biologic and clinical review. Chir Organi Mov. 2009;93 (1): 1-7. doi:10.1007/s12306-009-0016-4 - Pubmed citation
- 4. Jaffe HL. Tumors and tumorous conditions of the bones and joints. Philadelphia: Lea & Febiger; 1958. pp. 117–141.
- 5. Campanacci M, Laus M, Boriani S. Multiple non-ossifying fibromata with extraskeletal anomalies: a new syndrome?. J Bone Joint Surg Br. 1984;65 (5): 627-32. Pubmed citation
- 6. Mirra JM, Gold RH, Rand F. Disseminated nonossifying fibromas in association with café-au-lait spots (Jaffe-Campanacci syndrome). Clin. Orthop. Relat. Res. 1982; (168): 192-205. Pubmed citation
- 7. Vannelli S, Vannelli BR, Vannelli RF, Vannelli MI, Vannelli AA, Vannelli dSL, Vannelli. Jaffe-Campanacci syndrome or neurofibromatosis type 1: a case report of phenotypic overlap with detection of NF1 gene mutation in non-ossifying fibroma. (2020) Italian journal of pediatrics. doi:10.1186/s13052-020-0813-9 - Pubmed