Jejunoileal bypass is an older form of bariatric surgery that was developed to be an improvement on jejunocolic bypass. It is no longer performed due to severe side effects.
This has been performed with both end-to-side and end-to-end anastomoses. In the end-to-end anastomosis, the excluded small bowel is anastomosed to the colon.
The bypass was designed to treat obesity by malabsorption of ingested food.
Treatment and prognosis
Although the end-to-end anastomosis is effective in achieving short-term weight loss 2, the procedure has several side effects:
- bacterial overgrowth in the blind loop anastomosed to the colon ("bypass enteritis")
- lactose intolerance
- absorption of bacterial toxins leading to polyarthralgia and hepatic failure
- continuous diarrhea
- anal excoriation and hemorrhoids
- short gut syndrome with nutrient malabsorption and multiple systemic side effects from malnutrition
- paradoxically resulted in increased carbohydrate absorption, leading to regain of weight
Mortality rate in the first two years is ~4%, mostly from liver failure 3.
- 1. Moshiri M, Osman S, Robinson TJ et-al. Evolution of bariatric surgery: a historical perspective. AJR Am J Roentgenol. 2013;201 (1): W40-8. doi:10.2214/AJR.12.10131 - Pubmed citation
- 2. Deitel M. Overview of operations for morbid obesity. World J Surg. 1998;22 (9): 913-8. Pubmed citation
- 3. Scott HW, Dean RH, Shull HJ et-al. Metabolic complications of jejunoileal bypass operations for morbid obesity. Annu. Rev. Med. 1976;27 (1): 397-405. doi:10.1146/annurev.me.27.020176.002145 - Pubmed citation