Jugular fossa masses
Jugular fossa masses comprise a range of pathological lesions that arise from or extend into the jugular fossa in the skull base. Although not a common location for tumours it is not unusual for jugular fossa lesions to be discovered incidentally on cross sectional imaging.
Although the jugular foramen is technically an anatomically distinct entity which connects the jugular fossa to the posterior fossa, both contain the same neurovascular structures and lesions present similarly. As the differential for lesions arising here are the same, for the purposes of this article the terms jugular fossa and jugular foramen will be used interchangeably.
Although the exact underlying pathology varies most jugular fossa tumours are slow growing and can cause symptoms by compressing the nerves that lie within the fossa. Symptoms can include:
- loss of taste posterior one third of the tongue
- glossopharyngeal nerve palsy (CN IX)
vocal cord paralysis and absent gag reflex
- vagus nerve palsy (CN X)
- weakness of the trapezius and sternocleidomastoid muscles
- accessory nerve palsy (CN XI)
When there is unilateral palsy of the 9th-11th cranial nerves this is termed as jugular foramen syndrome.
However, the most common symptoms tend to arise from expansion into the middle ear:
Involvement of the inner ear can lead to vertigo and sensorineural hearing loss.
Symptoms of raised intracranial compression can develop if there is significant intracranial extension of the underlying tumour.
The most common lesion seen involving the jugular fossa is a glomus jugulare paraganglioma followed by schwannomas and meningiomas.2
Jugular fossa masses can broadly be classified as extrinsic or intrinsic. Occasionally, pseudotumours can arise as a result of:
- CSF leak due to trauma
- jugular bulb flow variation
Intrinsic masses arise from the the structures that traverse the jugular fossa:
Extrinsic masses arise from the surrounding tissues around the jugular fossa and extend into it:
- glial cell tumours
- inflammatory lesions
- temporal bone tumours
- primary cholesteatoma
- epidermoid tumours
- choroid plexus papilloma
While contrast MRI better at defining the nature of jugular fossa lesions CT is superior in assessing any involvement of the adjacent bony structures.
- 1. Vogl TJ, Bisdas S. Differential diagnosis of jugular foramen lesions. Skull Base. 2009;19 (01): 3-16. doi:10.1055/s-0028-1103121 - Free text at pubmed - Pubmed citation
- 2. Ramina R, Maniglia JJ, Fernandes YB et-al. Jugular foramen tumors: diagnosis and treatment. Neurosurg Focus. 2005;17 (2): E5. Pubmed citation
- 3. SVIEN HJ, BAKER HL, RIVERS MH. JUGULAR FORAMEN SYNDROME AND ALLIED SYNDROMES. Neurology. 1996;13: 797-809. Pubmed citation
- 4. Robbins KT, Fenton RS. Jugular foramen syndrome. J Otolaryngol. 1981;9 (6): 505-16. Pubmed citation
- 5. Ramina R, Maniglia JJ, Fernandes YB et-al. Jugular foramen tumors: diagnosis and treatment. Neurosurg Focus. 2005;17 (2): E5. Pubmed citation
- 6. Weber AL, McKenna MJ. Radiologic evaluation of the jugular foramen. Anatomy, vascular variants, anomalies, and tumors. Neuroimaging Clin. N. Am. 1994;4 (3): 579-98. Pubmed citation