Juvenile idiopathic arthritis
Juvenile idiopathic arthritis (JIA), also known as juvenile rheumatoid arthritis or Still disease, is the most common chronic arthritic disease of childhood and has multiple subtypes.
The estimated incidence is ~13 per 100,000 per annum 3.
Oligoarticular or polyarticular arthritis of a duration of six weeks or longer must be present to diagnose JIA.
Patients may present with an acute onset of symptoms or a more gradual onset. Symptoms are often worse in the morning, but typically persist to some extent throughout the day.
In patients with systemic onset, intermittent spiking fevers are typically noted, which help distinguish JIA from other diseases such as infection, other inflammatory diseases and malignancy. A light pink rash involving the trunk and/or extremities is also frequently observed in patients with systemic onset.
Imaging shows a varied spectrum of involvement, based on the severity and duration of the disease.
MRI shows synovial hypertrophy, joint effusions as well as osseous and cartilaginous erosions. Active synovitis is characterized by enhancement on T1-weighted gadolinium contrast studies.