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Juxta-cortical chondrosarcoma

A.Prof Frank Gaillard ◉ ◈ et al.

Juxta-cortical chondrosarcomas, also known as periosteal chondrosarcomas, are indistinguishable histologically from conventional medullary chondrosarcomas and are therefore graded into low, intermediate or high-grade tumors (see chondrosarcoma grading).

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Article:

Epidemiology
Pathology
Differential diagnosis
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References

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Cases and figures

Epidemiology

Typically it occurs in adults in their 3^rdand 4^th decades and is slightly more frequent in males.

Pathology

Unlike conventional chondrosarcomas, they arise from the surface of the bone, lifting the periosteum over themselves as a fibrous pseudocapsule. The underlying cortex is usually thickened or may be eroded, however, extension into the medullary cavity is not usual. Where the periosteum is lifted a Codman triangle may be seen. In addition to the usual chondroid matrix, metaplastic ossification is also common.

Location

They typically arise from long bones, with a predilection for the posterior aspect of the distal femur.

Differential diagnosis

periosteal osteosarcoma
- affects younger patients (typically 10-25 years of age)
- periosteal reaction perpendicular to the cortex
- diaphyseal rather than metaphyseal
parosteal osteosarcoma
- stalk of bony attachment
- otherwise similar appearance, location and demographics
juxtacortical chondroma
parosteal lipoma

References

Bone tumours

The differential diagnosis for bone tumors is dependent on the age of the patient, with a very different set of differentials for the pediatric patient.

bone tumors
- bone-forming tumors
- cartilage-forming tumors
- fibrous bone lesions
- bone marrow tumors
- other bone tumors or tumor-like lesions
- skeletal metastases
  - morphology
  - location
  - impending fracture risk
    - Harrington criteria
    - Mirel classification
- staging
  - AJCC staging of musculoskeletal tumors
  - Enneking surgical staging system

Article information

rID: 6195

System: Musculoskeletal

Synonyms or Alternate Spellings:

Periosteal chondrosarcoma
Juxta-cortical chondrosarcomas
Periosteal chondrosarcomas

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Cases and figures

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