Killian dehiscence
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At the time the article was created Omoleye, Olasubomi Jimmy had no recorded disclosures.
View Omoleye, Olasubomi Jimmy's current disclosuresAt the time the article was last revised Yvette Mellam had no financial relationships to ineligible companies to disclose.
View Yvette Mellam's current disclosures- Killian's triangle
- Killian-Jamieson triangle
- Jamieson triangle
- Pharyngeal dimple
- Killian's dehiscence
- Killian triangle
The Killian dehiscence is a triangular-shaped area of weakness in the muscular wall of the pharynx, between the transverse and oblique bundles of the inferior pharyngeal constrictor 1. It is the most common site of pharyngeal diverticula 5.
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Gross anatomy
It is located in the posterior wall of the laryngopharynx, slightly above the origin of the esophagus 1.
The Killian dehiscence is a triangular area of weakness formed by the oblique fibers of the inferior pharyngeal constrictor (thyropharyngeus), which attach anteriorly to the oblique lamina at the sides of the thyroid cartilage and posteriorly to the median raphe, and the transverse fibers of the inferior pharyngeal constrictor (cricopharyngeus), which attach to the sides of the cricoid cartilage anteriorly and wind around the pharynx, with no posterior attachment 1,2.
Internal to the inferior constrictor, the relatively strong pharyngobasilar fascia forms the submucosal lining. A relatively weaker buccopharyngeal fascia forms the external lining of the inferior constrictor 2.
Variant anatomy
While not anatomically evident in every individual, it has been found to occur more commonly in males 3. The dimensions of Killian's triangle of weakness have also been shown to correlate with individual anthropometric parameters, consequently being more prominent in males than in females 3.
One study suggests that it is present in ~60% of males, and just ~30% of females 3. This could explain why pharyngeal pouches are more common in males.
Development
Killian dehiscence arises due to the descent of the larynx during development 4. As the pharyngeal constrictors (apart from cricopharyngeus) are attached to the median raphe, which in turn is attached to the skull base, laryngeal descent during development causes the constrictors to assume an oblique course, leaving cricopharyngeus in a transverse orientation, thus creating a potential area of weakness 4.
History and etymology
It is named after Gustav Killian (1860-1921) a German otolaryngologist.
Related pathology
Uncoordinated contraction of the inferior pharyngeal constrictor and spasm, or fibrosis, of cricopharyngeus, have been implicated in the formation of pharyngeal pouches (Zenker diverticula), due to the increased intraluminal pressures these cause during swallowing. The increased intraluminal pressures then lead to herniation through this potential area of weakness 1,5.
Killian dehiscence is the most common site of pharyngeal diverticula 5.
References
- 1. Harold Ellis, Vishy Mahadevan. Clinical Anatomy. (2010) ISBN: 9781405186179
- 2. Keith L. Moore, Arthur F. Dalley, A. M. R. Agur. Clinically Oriented Anatomy. (2013) ISBN: 9781451119459
- 3. Anagiotos A, Preuss SF, Koebke J. Morphometric and anthropometric analysis of Killian's triangle. (2010) The Laryngoscope. 120 (6): 1082-8. doi:10.1002/lary.20886 - Pubmed
- 4. Michael C. Joiner, Albert van der Kogel. Basic Clinical Radiobiology, Fifth Edition. (2016) ISBN: 9780340808931
- 5. Killian's dehiscence - an overview. Science Direct (2018).
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