Knuckle sign refers to the abrupt tapering or cutoff of a pulmonary artery secondary to embolus. It is better visualised on CT pulmonary angiography scan than chest x-ray. This is an important ancillary finding in pulmonary embolism (PE), and often associated with the Fleischner sign of dilated central pulmonary arteries.
It is one of several described signs of pulmonary embolus on chest radiographs.
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