Lady Windermere syndrome

Lady Windermere syndrome refers to a pattern of pulmonary Mycobacterium avium complex (MAC) infection seen typically in elderly white women who chronically suppress the normal cough reflex. A fastidious nature and a reticence to expectorate are believed to predispose such persons to infections with MAC.

Radiographic features

Plain radiograph

Linear opacities in middle lobe or lingula can be seen, as a result of subsegmental atelectasis or bronchiectasis with mucosal impactions. Residual middle lobe or lingula atelectasis can also be seen.


Typical manifestation is of bronchiectasis, centrilobular nodules and eventual scarring and volume loss affecting the middle lobe and lingula 1

It is one of the causes of right middle lobe syndrome

History and etymology

The syndrome is named after Lady Windermere, a character in Oscar Wilde's 1892 play Lady Windermere's fan 2.

Article information

rID: 9281
System: Chest
Section: Syndromes
Synonyms or Alternate Spellings:
  • Lady Windermere's syndrome

ADVERTISEMENT: Supporters see fewer/no ads

Cases and figures

  • Case 1
    Drag here to reorder.
  • Case 2
    Drag here to reorder.
  • Updating… Please wait.

     Unable to process the form. Check for errors and try again.

     Thank you for updating your details.