Lady Windermere syndrome

Last revised by Sonam Vadera ◉ on 13 May 2022

Citation, DOI, disclosures and article data

Citation:

Gaillard F, Vadera S, Lorente E, et al. Lady Windermere syndrome. Reference article, Radiopaedia.org (Accessed on 02 Jun 2023) https://doi.org/10.53347/rID-9281

DOI:

https://doi.org/10.53347/rID-9281

Permalink:

https://radiopaedia.org/articles/9281

rID:

9281

Article created:

28 Mar 2010, Frank Gaillard ◉ ◈

Disclosures:

At the time the article was created Frank Gaillard had no recorded disclosures.

View Frank Gaillard's current disclosures

Last revised:

13 May 2022, Sonam Vadera ◉

Disclosures:

At the time the article was last revised Sonam Vadera had no recorded disclosures.

View Sonam Vadera's current disclosures

Revisions:

15 times, by 10 contributors - see full revision history and disclosures

Systems:

Chest

Sections:

Syndromes

Tags:

syndrome

Synonyms:

Lady Windermere's syndrome

Lady Windermere syndrome refers to a pattern of pulmonary Mycobacterium avium complex (MAC) infection seen typically in elderly white women who chronically suppress the normal cough reflex. A fastidious nature and a reticence to expectorate are believed to predispose such persons to infections with MAC.

Radiographic features

Plain radiograph

Linear opacities in middle lobe or lingula can be seen, as a result of subsegmental atelectasis or bronchiectasis with mucosal impactions. Residual middle lobe or lingula atelectasis can also be seen.

CT

Typical manifestation is of bronchiectasis, centrilobular nodules, tree-in-bud nodularity and eventual scarring and volume loss affecting the middle lobe and lingula ¹.

It is one of the causes of right middle lobe syndrome.