Laser interstitial thermal therapy
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At the time the article was created Francis Deng had no recorded disclosures.View Francis Deng's current disclosures
At the time the article was last revised Francis Deng had no recorded disclosures.View Francis Deng's current disclosures
Laser interstitial thermal therapy (LITT) or focal laser ablation is a surgical technique for selective ablation of a lesion or tissue using laser-generated heat. Compared to other minimally invasive techniques such as radiofrequency, microwave, or cryoablation, lasers are able to create a more precise ablation zone 1.
MRI-guided laser interstitial thermal therapy has thus far gained clinical use primarily in neurosurgical applications, such as treatment of brain tumors and epilepsy 1, and urological applications such as treatment of prostate cancer 2. MRI is employed for stereotactic navigation of probe placement as well as intraoperative thermal imaging of the ablation area. Postprocedural imaging evaluates the extent of ablation 1,3.
- 1. Salem U, Kumar VA, Madewell JE, Schomer DF, de Almeida Bastos DC, Zinn PO, Weinberg JS, Rao G, Prabhu SS, Colen RR. Neurosurgical applications of MRI guided laser interstitial thermal therapy (LITT). (2019) Cancer imaging : the official publication of the International Cancer Imaging Society. 19 (1): 65. doi:10.1186/s40644-019-0250-4 - Pubmed
- 2. Westin C, Chatterjee A, Ku E, Yousuf A, Wang S, Thomas S, Fan X, Eggener S, Karczmar G, Oto A. MRI Findings After MRI-Guided Focal Laser Ablation of Prostate Cancer. (2018) AJR. American journal of roentgenology. 211 (3): 595-604. doi:10.2214/AJR.17.19201 - Pubmed
- 3. Felker ER, Raman SS, Lu DSK, Tuttle M, Margolis DJ, ElKhoury FF, Sayre J, Marks LS. Utility of Multiparametric MRI for Predicting Residual Clinically Significant Prostate Cancer After Focal Laser Ablation. (2019) AJR. American journal of roentgenology. 213 (6): 1253-1258. doi:10.2214/AJR.19.21637 - Pubmed