Laser interstitial thermal therapy

Last revised by Francis Deng on 8 Apr 2021

Laser interstitial thermal therapy (LITT) or focal laser ablation is a surgical technique for selective ablation of a lesion or tissue using laser-generated heat. Compared to other minimally invasive techniques such as radiofrequency, microwave, or cryoablation, lasers are able to create a more precise ablation zone 1.

MRI-guided laser interstitial thermal therapy has thus far gained clinical use primarily in neurosurgical applications, such as treatment of brain tumors and epilepsy 1, and urological applications such as treatment of prostate cancer 2. MRI is employed for stereotactic navigation of probe placement as well as intraoperative thermal imaging of the ablation area. Postprocedural imaging evaluates the extent of ablation 1,3.

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