Lederer-Brill disease is a transient autoimmune hemolytic anemia with very variable clinical features 1.
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Epidemiology
Lederer-Brill disease is slightly more prevalent in females 1.
Clinical presentation
It usually occurs in children with a recent history of infection. Symptoms and signs include 1:
massive hemolysis resulting in anemia, jaundice, and hemoglobinuria
fever
lethargy
abdominal pain, nausea, vomiting