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Leontiasis ossea

Leontiasis ossea is largely a historical term used to describe a number of conditions that result in the affected patient's face resembling that of a lion. Although it is most frequently associated with craniofacial fibrous dysplasia, it has a broader meaning encompassing other lesions that have similar appearance 1,4

The distinction is made between true leontiasis ossea (craniofacial fibrous dysplasia) and other conditions having similar external appearance (mimics), however it would be safe to say that as a term it is no longer of clinical use and should be avoided. 

In addition to craniofacial fibrous dysplasia the following conditions may mimic leontiasis ossea:

History and etymology

The famed Virchow first coined the term leontiasis ossea in 1864 3Rudolf Ludwig Carl Virchow (1821-1902) was a German pathologist and statesman 5.

Article information

rID: 6570
System: Head & Neck
Section: Syndromes
Synonyms or Alternate Spellings:

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Cases and figures

  • Figure 1: a lion
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  • Case 1: fibrous dysplasia
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  • Figure 2: leontiasis ossea
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  • Case 1: fibrous dysplasia
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  • Case 2: fibrous dysplasia
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