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Leser-Trélat sign

The Leser-Trélat sign is a dermatological paraneoplastic syndrome referring to the explosive and rapid eruption of multiple seborrheic keratoses. It is associated with a number of different cancers including adenocarcinoma (e.g. gastric, colorectal), breast cancer, and lymphoproliferative disorders. The sign is a marker of advanced disease and is a poor prognostic marker 1.

Article information

rID: 65989
System: Oncology
Synonyms or Alternate Spellings:
  • Leser-Trelat sign of malignancy

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