Leukaemia (CNS manifestations)

Leukaemia CNS manifestations can be divided into those related to the disease itself and those associated with its treatment. Leukaemias are haematologic malignancies in which occur a proliferation of haematopoietic cells at an undifferentiated or partially differentiated stage of maturation 1.

CNS manifestations directly attributed to leukaemia
Leukaemia treatment-related CNS complications
  • chemotherapy
    • drug-induced PRES 1
    • methotrexate neurotoxicity
      • aseptic meningitis
      • transverse myelopathy
      • stroke-like syndrome
      • demyelination and leukoencephalopathy
    • CNS infections due immunosuppression (e.g. CNS aspergillosis and neurocandidiasis)
  • radiation therapy
  • bone marrow transplantation
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Article information

rID: 40055
Synonyms or Alternate Spellings:
  • CNS manifestations of leukaemia
  • Leukaemia: CNS complications
  • CNS complications of leukaemia

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