Leukemia testicular manifestations, or testicular leukemia, can be seen in patients during and after acute leukemia. The blood-testis barrier limits chemotherapy from reaching the testis, and therefore the testis can act as a sanctuary for leukemic cells.
- typically presents with painless testicular enlargement
- most commonly appears 2-3 years following primary disease but recurrence has been reported up to 19 years post initial diagnosis 3
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ultrasound appearance is often similar to testicular lymphoma, but it can have a very wide range of appearances:
- testicular enlargement
- unilateral or bilateral
- focal or diffuse
- hypoechoic to hyperechoic
- given the non-specific imaging features, clinical history is mandatory for a diagnosis
See also
- systemic involvement of leukemia