Leukoplakia of the urinary tract

Leukoplakia of the urinary tract is a squamous metaplasia of the urothelium (keratinisation). 

Clinically the condition presents with haematuria in one-third of cases, dysuria, frequency and nocturia, and thus it can mimic cystitis. Passage of the desquamated keratinised epithelial layers can also occur.

The condition is associated with infection in the majority of cases (80%) and calculi in 40%. It can occur in the bladder, the renal pelvis and the ureter (in this order of decreasing frequency).

Macroscopically, white patches may be seen (hence the name).

Mucosal thickening and multiple filling defects.

Leukoplakia is considered a premalignant condition. There is an association with bladder neoplasia in 25% of cases.

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Article information

rID: 27584
System: Urogenital
Section: Pathology
Synonyms or Alternate Spellings:
  • Leukoplakia of the urinary tract
  • Leukoplakia of the urinary tracts
  • Leukoplakia of urinary tracts

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