Li-Fraumeni syndrome

Li-Fraumeni syndrome is a hereditary cancer syndrome. Approximately half of affected individuals are thought to develop invasive cancer by 30 years of age 1.

Pathology

It is the result of mutations in the p53 tumour suppressor gene TP53. 

Associated malignancies
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Article Information

rID: 24568
Synonyms or Alternate Spellings:
  • Li-Fraumeni syndrome

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