Li-Fraumeni syndrome

Li-Fraumeni syndrome is a hereditary cancer syndrome due to mutations in the tumor suppressor gene TP53. Approximately half of affected individuals are thought to develop invasive cancer by 30 years of age 1.

Associated malignancies

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Article information

rID: 24568
Section: Syndromes
Synonyms or Alternate Spellings:
  • Li Fraumeni syndrome

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