Liddle syndrome

Liddle's syndrome is an autosomal dominant condition which inhibits the normal degradation of the ENaC sodium channel, resulting in findings that mimic Conn's syndrome (hyperaldosteronism); hypernatraemia, hypokalaemia and elevated serum bicarbonate. Typically patients are asymptomatic other than hypertension, which is hopefully identified in childhood. 

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Article information

rID: 5602
Synonyms or Alternate Spellings:
  • Liddle's syndrome

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