Linear energy transfer

Changed by Andrew Murphy , 22 Jul 2020

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Linear energy transfer (LET)is the average (radiation) energy deposited per unit path length along the track of an ionising particle. Its units are keV/μm.

Linear energy transfer describes the energy deposition density of a particular type of radiation, which largely determines the biological consequence of radiation exposure.

The LETlinear energy transfer of a chargedcharged particle2 is ∞ Q​2/Ek

  • LETlinear energy transfer is proportional to the square of the charge of the particle
  • LETlinear energy transfer is inversely proportional to the particle's kinetic energy
High LETlinear energy transfer radiations: LETlinear energy transfer 3-200 keV/μm
  • commonly mediated by:
  • greater density of interactions at cellular level
  • more likely, than low LETlinear energy transfer, to produce biological damage in a given volume of tissue
Low LETlinear energy transfer radiations: LETlinear energy transfer 0.2-3 keV/μm
  • commonly mediated by:
  • less likely than high LETlinear energy transfer to produce tissue damage in the same volume of tissue
  • -<p><strong>Linear energy transfer (LET)</strong> is the average (radiation) energy deposited per unit path length along the track of an <a href="/articles/ionising-radiation">ionising particle</a>. Its units are keV/μm.</p><p>Linear energy transfer describes the energy deposition density of a particular type of radiation, which largely determines the biological consequence of radiation exposure.</p><p>The LET of a <strong>charged </strong>particle<sup>2</sup> is ∞ Q<sup>​2</sup>/E<sub>k </sub></p><ul>
  • -<li>LET is proportional to the square of the charge of the particle</li>
  • -<li>LET is inversely proportional to the particle's kinetic energy</li>
  • -</ul><h6>High LET radiations: LET 3-200 keV/μm</h6><ul>
  • +<p><strong>Linear energy transfer </strong>is the average (radiation) energy deposited per unit path length along the track of an <a href="/articles/ionising-radiation">ionising particle</a>. Its units are keV/μm.</p><p>Linear energy transfer describes the energy deposition density of a particular type of radiation, which largely determines the biological consequence of radiation exposure.</p><p>The linear energy transfer of a charged<strong> </strong>particle<sup>2</sup> is ∞ Q<sup>​2</sup>/E<sub>k </sub></p><ul>
  • +<li>linear energy transfer is proportional to the square of the charge of the particle</li>
  • +<li>linear energy transfer is inversely proportional to the particle's kinetic energy</li>
  • +</ul><h6>High linear energy transfer radiations: linear energy transfer 3-200 keV/μm</h6><ul>
  • -<li>more likely, than low LET, to produce biological damage in a given volume of tissue</li>
  • +<li>more likely, than low linear energy transfer, to produce biological damage in a given volume of tissue</li>
  • -<br>Low LET radiations: LET 0.2-3 keV/μm</h6><ul>
  • +<br>Low linear energy transfer radiations: linear energy transfer 0.2-3 keV/μm</h6><ul>
  • -<li>less likely than high LET to produce tissue damage in the same volume of tissue</li>
  • +<li>less likely than high linear energy transfer to produce tissue damage in the same volume of tissue</li>

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