Lipoblastoma of lung
Lipoblastoma of the lung is a fat derived thoracic tumour.
They occur during infancy and early childhood. More than 90% of cases are diagnosed in children less than 3 years of age, with nearly 75% occurring before the age of 12 months
Lipoblastomas are rare soft-tissue mesenchymal tumours principally derived of embryonic white fat 3. They typically occur in the extremities (70% of cases), with the remainder of cases in mediastinal, retroperitoneal, or paravertebral areas. Occurrence in the lung is rare. They can also involve the chest wall or pleura
They may be divided into two categories:
- lipoblastoma: more common superficial well-defined mass
- lipoblastomatosis: deep, unencapsulated infiltrative lesion
Nonspecific findings - may be seen as a soft-tissue-opacity mass on plain radiographs.
Seen as a fat containing lesion with predominant intratumoral stranding.
Maybe useful in selected cases. A notable characteristic on MR imaging includes intratumoral streaks and whorls that correspond to the tumour’s fibrovascular network. Cystic changes can be seen. However, lipoblastomas lack the fluid or calcific components.
- myxoid liposarcomas may have a similar CT appearance but are relatively uncommon in children
- 1. Gaerte SC, Meyer CA, Winer-Muram HT et-al. Fat-containing lesions of the chest. Radiographics. 2002;22 Spec No (suppl_1): S61-78. doi:10.1148/radiographics.22.suppl_1.g02oc08s61 - Pubmed citation
- 2. Kanu A, Oermann CM, Malicki D et-al. Pulmonary lipoblastoma in an 18-month-old child: a unique tumor in children. Pediatr. Pulmonol. 2002;34 (2): 150-4. doi:10.1002/ppul.10144 - Pubmed citation
- 3. Hicks J, Dilley A, Patel D et-al. Lipoblastoma and lipoblastomatosis in infancy and childhood: histopathologic, ultrastructural, and cytogenetic features. Ultrastruct Pathol. 2002;25 (4): 321-33. Pubmed citation
- 4. Mathew J, Sen S, Chandi SM et-al. Pulmonary lipoblastoma: a case report. Pediatr. Surg. Int. 2002;17 (7): 543-4. Pubmed citation