Liquefactive necrosis is a form of necrosis where there is transformation of the tissue into a liquid viscous mass.
In liquefactive necrosis, the affected cell is completely digested by hydrolytic enzymes leading to a soft, circumscribed lesion which can consist of fluid with remains of necrotic tissue or pus.
It is commonly associated with infection, dependent on the site of involvement.
Reported organs in which liquefactive necrosis is a recognized phenomenon include:
- 1. Burrell M, Gold JA, Simeone J, Taylor K, Dobbins J. Liquefactive necrosis of the pancreas: the pancreatic sac. Radiology. 135 (1): 157-60. doi:10.1148/radiology.135.1.7360954 - Pubmed
- 2. Downer WR, Peterson MS. Massive splenic infarction and liquefactive necrosis complicating polycythemia vera. AJR. American journal of roentgenology. 161 (1): 79-80. doi:10.2214/ajr.161.1.8517327 - Pubmed
- 3. Estes ML, Rorke LB. Liquefactive necrosis in Coxsackie B encephalitis. Archives of pathology & laboratory medicine. 110 (11): 1090-2. Pubmed
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Terms used in radiology
- fluid collection
- granulation tissue