Liquefactive necrosis

Last revised by Daniel J Bell on 21 Apr 2021

Liquefactive necrosis is a form of necrosis where there is transformation of the tissue into a liquid viscous mass.


In liquefactive necrosis, the affected cell is completely digested by hydrolytic enzymes leading to a soft, circumscribed lesion which can consist of fluid with remains of necrotic tissue or pus.

It is commonly associated with infection, dependant on the site of involvement.


Reported organs in which liquefactive necrosis is a recognized phenomenon include:

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