Syphilitic aortitis takes place during the stage of tertiary syphilis between 5 to 30 years after initiation of primary syphilis. This is normally due to infection of aorta secondary to endarteritis obliterans of vasa-vasorum.
Aortic wall becomes progressively weakened due to chronic inflammation. This will subsequently lead to aneurysm (10%), coronary artery narrowing at ostium (30%) and aortic valve insufficiency secondary to the involvement of aortic valve.
- extensive thickening of aortic wall with peri-aortic inflammation
- asymmetrical aortic sinus involvement
- saccular aneurysms and heavily calcified ascending aorta
- "tree bark" intimal calcifications due to intimal wrinkling
- saccular asymmetric aortic aneurysm
- aortic root branches involvement
The aneurysm diameter is often not accurately measured by using angiography. This is normally due to intra-aneurysmal / mural thrombosis and calcification, layering of the contrast and magnification.
Treatment and prognosis
High-dose antibiotics and resection of enlarging aneurysm.
History and etymology
The term "Lues" is an old name for syphilis, derived from Latin lues for "filth".
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- acute aortic syndrome
- thoracic aortic aneurysm
- abdominal aortic aneurysm
- endovascular aneurysm repair (EVAR)
- reporting tips for aortic aneurysms
- aortic coarctation
- aortic pseudocoarctation
- cervical aortic arch
- interrupted aortic arch
- transposition of the great arteries
- variant anatomy of the aortic arch
- traumatic aortic injuries