Lymphatic drainage of the breast
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Lymphatic drainage of breast originates from breast lobules and flows through intramammary nodes and channels into a subareolar plexus, called Sappey’s plexus. From this plexus, lymphatic drainage takes place through three main routes that parallel venous tributaries. Lymphatics from the left breast ultimately drain via the thoracic duct into the angle of the left subclavian and internal jugular vein, while the right breast drains via the right lymphatic duct into the angle of the right subclavian and internal jugular vein.
axillary or lateral pathway
dominant pathway (receives >75% of lymph from breasts)
drains all quadrants of the breast, with higher proportion of drainage from lateral quadrants, especially the upper outer quadrant 9
drains directly or via Sappey's plexus to axillary nodes
either runs around inferior border of pectoralis major to reach the pectoral group of lymph nodes or pass directly to the subscapular group
few channels from superior breast to the apical group sometimes interrupted by the infraclavicular group of lymph nodes
internal mammary pathway
drains all quadrants of the breast, with higher proportion of drainage from medial quadrants, especially the lower inner quadrant 9
passes through the intercostal spaces and pectoralis major into parasternal/internal mammary lymph nodes
connections may lead across the median plane and hence to the contralateral breast
comes from the deeper portion of the breast
contributes to a minor pathway relative to the others 9
drains to the subclavicular plexus
Other pathways occur when usual channels are blocked in disease. Lymph may pass to the contralateral breast, cervical nodes, peritoneal cavity and liver through the diaphragm or through the rectus sheath.
Compared to non-palpable breast lesions, palpable breast lesions more frequently drain via the internal mammary pathway 9.
Axillary lymph nodes can be divided into surgical levels:
level 1: lying below pectoralis minor
level 2: lying behind pectoralis minor
level 3: lying between the upper border of pectoralis minor and lower border of the clavicle