Lymphocytic mastitis
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View Henry Knipe's current disclosuresAt the time the article was last revised Henry Knipe had no recorded disclosures.
View Henry Knipe's current disclosures- Lymphocytic mastopathy
- Sclerosing lymphocytic lobulitis
Lymphocytic mastitis, also known as lymphocytic mastopathy or sclerosing lymphocytic lobulitis, is a rare benign inflammatory disease of the breast that can mimic breast cancer.
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Terminology
Diabetic mastopathy is a closely-related entity although it is sometimes used synonymously in the literature.
Clinical presentation
Lymphocytic mastitis may present as a palpable mass, which may be painful and may be bilateral.
Pathology
Lymphocytic mastitis is associated with autoimmune disease (e.g. Hashimoto thyroiditis, systemic lupus erythematosus, Sjogren syndrome) 1.
Macroscopic appearance
Dense fibrous tissue with hard lesions, that can be large (up to 6 cm) 4.
References
- 1. Sabaté JM, Clotet M, Gómez A et-al. Radiologic evaluation of uncommon inflammatory and reactive breast disorders. Radiographics. 2005;25 (2): 411-24. doi:10.1148/rg.252045077 - Pubmed citation
- 2. Alhabshi SM, Rahmat K, Westerhout CJ et-al. Lymphocytic mastitis mimicking breast carcinoma, radiology and pathology correlation: review of two cases. Malays J Med Sci. 2013;20 (3): 83-7. Free text at pubmed - Pubmed citation
- 3. Valdez R, Thorson J, Finn WG et-al. Lymphocytic mastitis and diabetic mastopathy: a molecular, immunophenotypic, and clinicopathologic evaluation of 11 cases. Mod. Pathol. 2003;16 (3): 223-8. doi:10.1097/01.MP.0000056627.21128.74 - Pubmed citation
- 4. Moinfar F. Essentials of Diagnostic Breast Pathology. Springer. ISBN:354045117X. Read it at Google Books - Find it at Amazon
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