Lymphomatoid granulomatosis

Lymphomatoid granulomatosis, also known as angiocentric lymphoma or angiocentric immunoproliferative lesion, is a rare type of non-Hodgkin's lymphoma associated with Epstein-Barr virus infection. 

There is a recognized association with antecedent infection with the Epstein Barr virus (EBV).  

It can affect a variety of organs: 

  • lung involvement: ~80% of cases 4
  • skin (cutaneous) involvement: 33-50% 2,4
  • CNS involvement: 20% 2

Radiographic features are discussed separately: 

It was initially described by Leibow et al. in 1972 5.


Article information

rID: 8869
Synonyms or Alternate Spellings:
  • Lymphomatoid granulomatosis
  • Angiocentric lymphoma
  • Angiocentric immunoproliferative lesion
  • Lymphomatoid granulomatosis (LG)

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