Lymphomatoid granulomatosis

Dr Henry Knipe and Dr Yuranga Weerakkody et al.

Lymphomatoid granulomatosis (LG), also known as angiocentric lymphoma or angiocentric immunoproliferative lesion, is a rare type of non-Hodgkin's lymphoma.

There is a recognised association with antecedent infection with the Epstein Barr virus (EBV).  

It can affect a variety of organs. 

  • lung involvement: ~80% of cases
  • skin (cutaneous) involvement: 33-50% 2,4
  • CNS involvement: 20% 2

Radiographic features are discussed separately: 

It was Initially described by Leibow et al in 1972 5.

Lymphoma
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Article information

rID: 8869
Section: Pathology
Tag: cases
Synonyms or Alternate Spellings:
  • Lymphomatoid granulomatosis
  • Angiocentric lymphoma
  • Angiocentric immunoproliferative lesion
  • Lymphomatoid granulomatosis (LG)

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