Citation, DOI, disclosures and article data
Citation:
Bell D, Lymphopenia. Reference article, Radiopaedia.org (Accessed on 13 Mar 2025) https://doi.org/10.53347/rID-75600
Lymphopenia (also known as lymphocytopenia, hypolymphemia and sublymphemia) is a deficiency of circulating lymphocytes 1. It may be either primary or secondary.
Terminology
The spelling lymphopaenia is erroneous and should never be used.
Pathology
Etiology
Primary
Secondary
- infections (commonest cause)
- mycobacteria: predominantly TB
- viral
- parasites
- malignancy
- autoimmune
- drugs
- steroids
- chemotherapeutic agents
- cytotoxics
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1. William Alexander Newman Dorland. Dorland's Illustrated Medical Dictionary. (2018) ISBN: 9781416023647
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2. Asher I, Mahlab-Guri K, Elbirt D, Ezalel-Rosenberg S, Sthoeger Z. Idiopathic CD4 Lymphopenia: Severe CD4 Lymphopenia in the Absence of Human Immunodeficiency Virus Infection. (2016) The Israel Medical Association journal : IMAJ. 18 (10): 627-629. Pubmed
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3. Picard C, Al-Herz W, Bousfiha A, Casanova JL, Chatila T, Conley ME, Cunningham-Rundles C, Etzioni A, Holland SM, Klein C, Nonoyama S, Ochs HD, Oksenhendler E, Puck JM, Sullivan KE, Tang ML, Franco JL, Gaspar HB. Primary Immunodeficiency Diseases: an Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency 2015. (2015) Journal of clinical immunology. 35 (8): 696-726. doi:10.1007/s10875-015-0201-1 - Pubmed
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