Lynch syndrome (mnemonic)

Last revised by Yaïr Glick on 31 Jul 2024

Citation, DOI, disclosures and article data

Citation:

Li S, Glick Y, Lynch syndrome (mnemonic). Reference article, Radiopaedia.org (Accessed on 11 Oct 2024) https://doi.org/10.53347/rID-192809

DOI:

https://doi.org/10.53347/rID-192809

Permalink:

https://radiopaedia.org/articles/192809

rID:

192809

Article created:

31 Jul 2024, Simon Li

Disclosures:

At the time the article was created Simon Li had no financial relationships to ineligible companies to disclose.

Last revised:

31 Jul 2024, Yaïr Glick ◉

Disclosures:

At the time the article was last revised Yaïr Glick had no financial relationships to ineligible companies to disclose.

Revisions:

3 times, by 2 contributors - see full revision history and disclosures

Lynch syndrome can be remembered using the mnemonic:

Right-handed C3PO is hollow

Of note, Mr. Lynch was the puppeteer for C3PO in Star Wars.

Related malignancies are listed in descending order of frequency with their percentage lifetime risk listed in parentheses.

C: colorectal cancer (10-82% lifetime risk, 70% right-sided)
3: endometrial cancer: (15-60%)
P: prostate cancer: (30%)
O: ovarian tumor: (4-12%)
Hollow structures: urothelial tract (1-7%), small bowel (5%), gastric (6-13%), hepatobiliary tract (1-4%), pancreatic (1-6%)