M-line of Cremin is an imaginary line that can be used to determine the level at which the blind pouch ends in anal atresia, determining whether the anal atresia is a high or a low type.
The line is drawn perpendicular to the long axis of the ischium on the lateral view and passes through the junction of the middle and lower third of the bone. In high type anal atresia, the pouch ends above the line, while if it ends below the line it is a low type anal atresia 1.