Paediatric malignant liver tumours are rare, some of which occur only in children but that are similar to those that occur in adults.
Malignant liver tumours account for ~1% of paediatric malignancies 2.
Broadly, any malignant liver mass can be defined as a metastasis or primary liver tumour. The commonest source of paediatric liver metastases is neuroblastoma 1.
Primary malignant hepatic neoplasms in children can broadly be classified by their cell of origin 1:
- epithelial (hepatocyte-derived)
An understanding of the clinicopathologic features of these neoplasms and how these features affect their imaging appearance helps the radiologist offer an appropriate differential diagnosis for a child with a liver mass.
- 1. Chung EM, Lattin GE, Cube R et-al. From the archives of the AFIP: Pediatric liver masses: radiologic-pathologic correlation. Part 2. Malignant tumors. Radiographics. 31 (2): 483-507. doi:10.1148/rg.312105201 - Pubmed citation
- 2. Litten JB, Tomlinson GE. Liver tumors in children. Oncologist. 2008;13 (7): 812-20. doi:10.1634/theoncologist.2008-0011 - Pubmed citation