Malignant liver tumours (paediatric)
Paediatric malignant liver tumours are rare, some of which occur only in children but that are similar to those that occur in adults.
Malignant liver tumours account for ~1% of paediatric malignancies 2.
Broadly, any malignant liver mass can be defined as a metastasis or primary liver tumour. The commonest source of paediatric liver metastases is neuroblastoma 1.
Primary malignant hepatic neoplasms in children can broadly be classified by their cell of origin 1:
- epithelial (hepatocyte-derived)
An understanding of the clinicopathologic features of these neoplasms and how these features affect their imaging appearance helps the radiologist offer an appropriate differential diagnosis for a child with a liver mass.
- 1. Chung EM, Lattin GE, Cube R et-al. From the archives of the AFIP: Pediatric liver masses: radiologic-pathologic correlation. Part 2. Malignant tumors. Radiographics. 31 (2): 483-507. doi:10.1148/rg.312105201 - Pubmed citation
- 2. Litten JB, Tomlinson GE. Liver tumors in children. Oncologist. 2008;13 (7): 812-20. doi:10.1634/theoncologist.2008-0011 - Pubmed citation