Malignant transformation

Dr Daniel J Bell et al.

Malignant transformation is the term given to the process whereby either normal, metaplastic, or benign neoplastic tissue, becomes a cancer. The process usually occurs in a series of steps and the affected tissue gradually accumulates the genetic mutations that express a malignant phenotype. The genetic steps are gradually being elucidated 1.

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Article information

rID: 61898
System: Oncology
Section: Pathology
Synonyms or Alternate Spellings:
  • Malignancy transformation
  • Cancer transformation
  • Transformation to cancer

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