Malignant transformation

Last revised by Mohammadtaghi Niknejad on 17 Jan 2023

Malignant transformation is the term given to the process whereby either normal, metaplastic, or benign neoplastic tissue, becomes a cancer. The process usually occurs in a series of steps and the affected tissue gradually accumulates the genetic mutations that express a malignant phenotype. The genetic steps are gradually being elucidated 1.

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Cases and figures

  • Case 1: gastrointestinal stromal tumor of stomach with malignant transformation
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  • Case 2: malignant cystic ovarian teratoma
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