Malignant transformation

Last revised by Mohammadtaghi Niknejad ◉ on 17 Jan 2023

Citation, DOI, disclosures and article data

Citation:

Bell D, Niknejad M, Malignant transformation. Reference article, Radiopaedia.org (Accessed on 30 May 2023) https://doi.org/10.53347/rID-61898

DOI:

https://doi.org/10.53347/rID-61898

Permalink:

https://radiopaedia.org/articles/61898?iframe=true

rID:

61898

Article created:

23 Jul 2018, Daniel J Bell ◉

Disclosures:

At the time the article was created Daniel J Bell had no recorded disclosures.

View Daniel J Bell's current disclosures

Last revised:

17 Jan 2023, Mohammadtaghi Niknejad ◉

Disclosures:

At the time the article was last revised Mohammadtaghi Niknejad had no financial relationships to ineligible companies to disclose.

View Mohammadtaghi Niknejad's current disclosures

Revisions:

2 times, by 1 contributor - see full revision history and disclosures

Systems:

Sections:

Synonyms:

Transformation to cancer
Cancer transformation
Malignancy transformation
Malignancy progression
Malignant progression

Malignant transformation is the term given to the process whereby either normal, metaplastic, or benign neoplastic tissue, becomes a cancer. The process usually occurs in a series of steps and the affected tissue gradually accumulates the genetic mutations that express a malignant phenotype. The genetic steps are gradually being elucidated ¹.

References

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Cases and figures

Case 1: gastrointestinal stromal tumor of stomach with malignant transformationCase 1: gastrointestinal stromal tumor of stomach with malignant transformation

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Case 2: malignant cystic ovarian teratomaCase 2: malignant cystic ovarian teratoma

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