It is decreased in conditions that either depress the floor of the third ventricle or change the position of the brain within the intracranial cavity. Such conditions include:
- intracranial hypotension: it is one of the helpful quantitative signs helpful in improving the accuracy of MRI diagnosis
- hydrocephalus: as one of the morphological changes at mid-sagittal MRI
The mamillopontine distance is measured on mid-sagittal T1WI MRI from the anterior root of the mamillary body to the top of the pons parallel to the anterior mesencephalon or the shortest distance between the centre of the mammillary bodies and the upper surface of the pons.
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- 2. Segev Y, Metser U, Beni-Adani L et-al. Morphometric study of the midsagittal MR imaging plane in cases of hydrocephalus and atrophy and in normal brains. AJNR Am J Neuroradiol. 2001;22 (9): 1674-9. AJNR Am J Neuroradiol (full text) - Pubmed citation