Man-in-the-barrel syndrome

Last revised by Maxime St-Amant on 27 Apr 2018

Man-in-the-barrel syndrome is a neurological syndrome characterized by bilateral brachial muscular weakness.


This syndrome is usually caused by bilateral cerebral lesions in the border zone between the anterior and middle cerebral arteries.


The syndrome has been described with multiple cerebral diseases including 1:

It has also been described with noncerebral diseases such as:

History and etymology

It was initially described by JP Mohr in 1969 as a brachial diplegia with normal motor function in the legs and face, giving the appearance of being constrained in a barrel 2.

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