Marbled pattern of the corpus callosum

A.Prof Frank Gaillard ◉ ◈ et al.

Marbled pattern of the corpus callosum has been described in the acute phase of neuromyelitis optica (NMO) and represents multiple overlapping lesions with heterogeneous signal ¹. This is distinct from the more typical appearance of multiple sclerosis (MS) where smaller separate individual lesions are seen ascending from the callososeptal interface.

References

Demyelination

demyelination
- primary demyelinating disorders
  - clinically isolated syndrome (CIS)
  - radiologically isolated syndrome (RIS)
  - multiple sclerosis (MS)
    - McDonald diagnostic criteria for MS (current 2017 revision)
      - previous 2016 MAGNIMS consensus
      - previous 2010 revision
      - previous 2001 - 2005 revisions
    - signs
    - variants
      - tumefactive multiple sclerosis
      - acute malignant Marburg type
      - Schilder type (diffuse cerebral sclerosis)
      - Balo concentric sclerosis (BCS)
      - opticospinal multiple sclerosis (OSMS)
  - neuromyelitis optica (NMO) (Devic disease)
    - signs
      - marbled pattern of the corpus callosum
      - longitudinally extensive spinal cord lesion (LESCL)
  - acute disseminated encephalomyelitis (ADEM) and acute haemorrhagic encephalomyelitis (AHEM)
  - tumefactive demyelinating lesions
  - transverse myelitis
  - chronic inflammatory demyelinating polyneuropathy (CIDP)
  - Guillain-Barre Syndrome (GBS)
    - acute inflammatory demyelinating polyradiculoneuropathy (AIDP)
    - axonal subtypes
      - acute motor axonal neuropathy (AMAN) (Chinese paralytic syndrome)
      - acute motor-sensory axonal neuropathy (AMSAN)
    - regional GBS syndromes
      - Miller Fisher variant
  - anti-MOG associated encephalomyelitis

Article information

rID: 26491

System: Central Nervous System

Synonyms or Alternate Spellings:

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