Marbled pattern of the corpus callosum

A.Prof Frank Gaillard ◉ ◈ et al.

Marbled pattern of the corpus callosum has been described in the acute phase of neuromyelitis optica (NMO) and represents multiple overlapping lesions with heterogeneous signal ¹. This is distinct from the more typical appearance of multiple sclerosis (MS) where smaller separate individual lesions are seen ascending from the callososeptal interface.

References

Demyelination

demyelination
- primary demyelinating disorders
  - clinically isolated syndrome (CIS)
  - radiologically isolated syndrome (RIS)
  - multiple sclerosis (MS)
    - McDonald diagnostic criteria for MS (2017 revision)
      - previous 2016 MAGNIMS consensus
      - previous 2010 revision
      - previous 2001 - 2005 revisions
    - signs
    - variants
      - tumefactive multiple sclerosis
      - acute malignant Marburg type
      - Schilder type (diffuse cerebral sclerosis)
      - Balo concentric sclerosis (BCS)
      - opticospinal multiple sclerosis (OSMS)
  - neuromyelitis optica (NMO) (Devic disease)
    - signs
      - marbled pattern of the corpus callosum
      - longitudinally extensive spinal cord lesion (LESCL)
  - acute disseminated encephalomyelitis (ADEM) and acute haemorrhagic encephalomyelitis (AHEM)
  - tumefactive demyelinating lesions
  - transverse myelitis
  - chronic inflammatory demyelinating polyneuropathy (CIDP)
  - Guillain-Barre Syndrome (GBS)
    - acute inflammatory demyelinating polyradiculoneuropathy (AIDP)
    - axonal subtypes
      - acute motor axonal neuropathy (AMAN) (Chinese paralytic syndrome)
      - acute motor-sensory axonal neuropathy (AMSAN)
    - regional GBS syndromes
      - Miller Fisher variant

Article information

rID: 26491

System: Central Nervous System

Synonyms or Alternate Spellings:

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.