Marbled pattern of the corpus callosum

A.Prof Frank Gaillard ◉ ◈ et al.

Marbled pattern of the corpus callosum has been described in the acute phase of neuromyelitis optica (NMO) and represents multiple overlapping lesions with heterogeneous signal ¹. This is distinct from the more typical appearance of multiple sclerosis (MS) where smaller separate individual lesions are seen ascending from the callososeptal interface.

References

White matter disorders

white matter
normal myelination
white matter disorders
- demyelination
  - anti-MOG associated encephalomyelitis
  - Guillain-Barre Syndrome (GBS)
    - acute inflammatory demyelinating polyradiculoneuropathy (AIDP)
    - axonal subtypes
      - acute motor axonal neuropathy (AMAN) (Chinese paralytic syndrome)
      - acute motor-sensory axonal neuropathy (AMSAN)
    - regional GBS syndromes
      - Miller Fisher variant
  - chronic inflammatory demyelinating polyneuropathy (CIDP)
  - transverse myelitis
  - tumefactive demyelinating lesions
  - acute disseminated encephalomyelitis (ADEM) and acute hemorrhagic encephalomyelitis (AHEM)
  - neuromyelitis optica (NMO) (Devic disease)
    - signs
      - marbled pattern of the corpus callosum
      - longitudinally extensive spinal cord lesion (LESCL)
  - multiple sclerosis (MS)
    - McDonald diagnostic criteria for MS (current 2017 revision)
      - previous 2016 MAGNIMS consensus
      - previous 2010 revision
      - previous 2001 - 2005 revisions
    - signs
    - variants
      - tumefactive multiple sclerosis
      - acute malignant Marburg type
      - Schilder type (diffuse cerebral sclerosis)
      - Balo concentric sclerosis (BCS)
      - opticospinal multiple sclerosis (OSMS)
  - radiologically isolated syndrome (RIS)
  - clinically isolated syndrome (CIS)
- dysmyelinating disorders
  - leukodystrophies
- hypomyelinating disorders

Article information

rID: 26491

System: Central Nervous System

Synonyms or Alternate Spellings:

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