Marcus Gunn pupil

Dr Amir Rezaee et al.

Marcus Gunn pupil, also known as afferent pupillary defect, is a nonspecific finding that indicates partial optic nerve dysfunction. It is mainly due to unilateral optic neuropathy, or rarely optic chiasm or optic tract lesions.

In response to light input to the affected eye, both eyes do not constrict to a normal extent but the affected pupil shows less constriction than the unaffected pupil. But if light is shone into the normal eye both eyes constrict normally and equally. It is because of a decrease in afferent input reaching the pretectal pathway responsible for the pupillary light response in the midbrain via damaged optic nerve, but efferent fibers to the affected eye are delivered via cranial nerve III.  

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Article Information

rID: 42406
Section: Signs
Tags: cases, refs
Synonyms or Alternate Spellings:

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