Marinacci anastomosis

Last revised by Rohit Sharma on 1 Mar 2025

Marinacci anastomosis, also known as reverse Martin-Gruber anastomosis, describes a rare interneural communication between the ulnar nerve and the median nerve in the distal forearm.

Most commonly, motor fibres from the ulnar nerve cross to join the median nerve in the distal forearm, the opposite to a Martin-Gruber anastomosis (thus 'reverse') 1,2. This is thought to be a very rare variant of the upper limb nerves, with a meta-analysis of cadaveric and electrophysiological studies suggesting a pooled frequency of less than 1% 1.

The anatomical variant was first described by American neurologist Albert A Marinacci in 1964 3.

The Marinacci anastomosis is generally not of clinical significance. When present, it is often only noted incidentally, usually during upper limb nerve conduction studies, and may confound accurate interpretation in that setting 2.

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