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Citation:
Bell D, Feger J, Matrix (bone). Reference article, Radiopaedia.org (Accessed on 29 Mar 2025) https://doi.org/10.53347/rID-99372
The matrix (plural: matrices) of the bone is used in a general pathological context to refer to the extracellular material in which the cellular components of the bone lie. Indeed the term extracellular matrix, often shortened to matrix, is used for the secreted extracellular components of any tissue in the body 1,2.
More specifically, matrix is also used as a descriptive term for radiology reports when referring to the contents of a bone lesion, particularly on plain radiography, but also on CT 3. For example, classically fibrous dysplasia of the bone has a ground glass matrix, whereas chondroid lesions tend to have a calcified matrix, e.g. chondrosarcoma.
See also
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1. Lin X, Patil S, Gao Y, Qian A. The Bone Extracellular Matrix in Bone Formation and Regeneration. Front Pharmacol. 2020;11:757. doi:10.3389/fphar.2020.00757 - Pubmed
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2. William Alexander Newman Dorland. Dorland's Illustrated Medical Dictionary. (2007) ISBN: 9781416023647 - Google Books
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3. Gerber E, Said-Hartley Q, Gamieldien R, Hartley T, Candy S. Accuracy of Plain Radiographs in Diagnosing Biopsy-Proven Malignant Bone Lesions. SA J Radiol. 2019;23(1):1768. doi:10.4102/sajr.v23i1.1768 - Pubmed
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