McBurney's point is defined as a point that lies one-third of distance laterally on a line drawn from the umbilicus to the right anterior superior iliac spine. Classically, it corresponds to the location of the base of the appendix 1.
Clinically, McBurney's point is relevant for the elicitation of McBurney's sign, which is deep tenderness at McBurney's point. This is key sign in the clinical assessment of appendicitis 1.
Charles McBurney was an American surgeon who located this point and published it in the New York Medical Journal in 1889 1.