Meningothelial meningioma

Meningothelial meningioma (also known as syncytial or endothelial meningiomas) is the most common histological subtype of meningioma, found in ~60% of all meningiomas, most frequently combined with fibrous meningioma (40%) or in isolation (17%) 1

Their epidemiology, clinical presentation, radiographic features, treatment, prognosis, and differential diagnosis are therefore discussed in the main article (see meningioma), and are not repeated here. 

Pathology

Meningothelial meningiomas most closely resemble arachnoid cap cells and are characterised by sheets, whorls or syncytia of neoplastic cells which have round or oval centrally located nuclei with dispersed chromatin, smooth nuclear profiles and small indistinct nucleoli. They also sometimes demonstrate eosinophilic cytoplasmic invaginations (a.k.a. intranuclear pseudoinclusions) 2-3. Lobules of tumour are separated from each other with collagen sheets 3

Share article

Article Information

rID: 42337
Section: Pathology
Tag: cases
Synonyms or Alternate Spellings:
  • Syncytial meningioma
  • Endothelial meningioma

Support Radiopaedia and see fewer ads

Cases and Figures

  • Drag
    Figure 1: intra-operative smear prep
    Drag here to reorder.
  • Drag
    Case 1: with abundant oedema
    Drag here to reorder.
  • Drag
    Case 2: with abundant oedema
    Drag here to reorder.
  • Drag
    Case 3
    Drag here to reorder.
  • Updating… Please wait.
    Loadinganimation

    Alert accept

    Error Unable to process the form. Check for errors and try again.

    Alert accept Thank you for updating your details.