The metabolic syndrome, also known as syndrome X, is a set of five conditions, which together increase a patient's risk of developing cardiovascular disease 1.
There are five central components of the metabolic syndrome:
It has been recognized for more than thirty years that the key metabolic phenomenon underlying the five elements of the metabolic syndrome is the development of insulin resistance 1.
The clinical diagnosis of metabolic syndrome relies upon measuring central adiposity, glucose tolerance, blood pressure and serum lipid levels.
History and etymology
The interconnectedness of these five entities was recognized decades ago, but the term metabolic syndrome was not coined until 1988 by Reaven in the annual Banting lecture 2.