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Metastases to testis

Dr Daniel J Bell ◉ and Dr Jeremy Jones ◉ et al.

Metastases to testis are a very rare cause of a testicular mass and may be bilateral in up to 15% of patients.

On this page:

Article:

Epidemiology
Pathology
See also
References

Epidemiology

Metastases to the testes are apparent in ~0.04% of autopsy studies in patients with known malignancy. The average age is 57 years, much older than the primary age for primary testicular cancer ².

Pathology

The literature suggests that the rarity of metastases to the testes may be due to:

lower temperature of the scrotum, so the malignant cells find it more difficult to proliferate ⁹
testes are a 'sanctuary' site - due to the blood-testicular barrier ¹⁰

Etiology

In adults a malignant testicular lesion is much more likely to be a primary. Even so-called common sources are rare. The largest series of 20 cases of metastases to the testes, over a ten-year period, found the majority to be from leukemia ¹⁰.

Common ⁹

leukaemia (most common) ⁸
lymphoma
prostate (most common solid tumor origin)
lung
colorectal cancer
renal cell carcinoma
malignant melanoma

Very rare

In children, sources include:

See also

References

Article information

rID: 9061

System: Urogenital, Oncology

Tag: cancer, metastases, cases

Synonyms or Alternate Spellings:

Testicular metastases
Metastasis to testicle
Metastasis to testis
Testicle metastases
Testicle metastasis
Testicular metastasis

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