Metastases to the vagina

Dr Henry Knipe and Dr Priya Cherian et al.

Metastases to the vagina are more common than primary vaginal malignancies, and account for >80% of vaginal tumors.


Metastases usually spread from contiguous sites most commonly, with lymphatic and hematogenous metastases also recognised.

Tumors that metastasise to the vagina include:

The location of the metastases that are adenocarcinomas can help determine origin, and a predominantly from the: 

  • upper genital tract if located within the anterior wall of the upper-third of the vagina
  • gastrointestinal tract if located within the posterior wall of the lower third of the vagina
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Article information

rID: 43415
Section: Pathology
Tags: refs, cases
Synonyms or Alternate Spellings:

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