Metastases to the vagina

Last revised by Rohit Sharma on 22 Feb 2018

Metastases to the vagina are more common than primary vaginal malignancies and account for >80% of vaginal tumors.


Metastases usually spread from contiguous sites most commonly, with lymphatic and hematogenous metastases also recognized.

Tumors that metastasize to the vagina include:

The location of the metastases that are adenocarcinomas can help determine the origin and are predominantly from the: 

  • upper genital tract if located within the anterior wall of the upper-third of the vagina
  • gastrointestinal tract if located within the posterior wall of the lower third of the vagina

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