Metastases to the vagina are more common than primary vaginal malignancies, and account for >80% of vaginal tumors.
Metastases usually spread from contiguous sites most commonly, with lymphatic and hematogenous metastases also recognised.
Tumors that metastasise to the vagina include:
The location of the metastases that are adenocarcinomas can help determine origin, and a predominantly from the:
- upper genital tract if located within the anterior wall of the upper-third of the vagina
- gastrointestinal tract if located within the posterior wall of the lower third of the vagina