Metastases to the vagina are more common than primary vaginal malignancies and account for >80% of vaginal tumors.
Pathology
Metastases usually spread from contiguous sites most commonly, with lymphatic and hematogenous metastases also recognized.
Tumors that metastasize to the vagina include:
The location of the metastases that are adenocarcinomas can help determine the origin and are predominantly from the:
- upper genital tract if located within the anterior wall of the upper-third of the vagina
- gastrointestinal tract if located within the posterior wall of the lower third of the vagina
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