Michel aplasia, also known as complete labyrinthine aplasia (CLA), is a congenital abnormality of the inner ear and is characterized by bilateral absence of differentiated inner ear structures with resultant anacusis. It should not be confused with Michel dysplasia.
Michel aplasia is thought to result from failure of development of the otic placode.
- abnormal development of the skeletal portions of the second arch
- skull base abnormalities
History and etymology
Michel aplasia was first described in 1863.
- 1. Marsot-Dupuch K, Dominguez-Brito A, Ghasli K et-al. CT and MR findings of Michel anomaly: inner ear aplasia. AJNR Am J Neuroradiol. 1999;20 (2): 281-4. AJNR Am J Neuroradiol (full text) - Pubmed citation
- 2. Ozgen B, Oguz KK, Atas A et-al. Complete labyrinthine aplasia: clinical and radiologic findings with review of the literature. AJNR Am J Neuroradiol. 2009;30 (4): 774-80. AJNR Am J Neuroradiol (full text) - doi:10.3174/ajnr.A1426 - Pubmed citation
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