Mickey Mouse sign (anencephaly)
Citation, DOI & article data
The Mickey Mouse sign in obstetric ultrasound denotes the characteristic "floating appearance" of the fetal cerebral lobes due to the absence of the cranium due to anencephaly.
The sign is best seen in the coronal plane (in relation to the fetal head), where the cerebral lobes are seen floating in the amniotic fluid above the orbits (like the ears of the mouse). According to one study this sign was present in 5 out of 6 anencephalic fetuses diagnosed between 12-14 weeks of gestation 1,2.
- 1. Chatzipapas I, Whitlow B, Economides D. The 'Mickey Mouse' Sign and the Diagnosis of Anencephaly in Early Pregnancy. Ultrasound Obstet Gynecol. 1999;13(3):196-9. doi:10.1046/j.1469-0705.1999.13030196.x - Pubmed
- 2. Hall J, Denne N, Minardi J, Williams D, Balcik B. Check the Head: Emergency Ultrasound Diagnosis of Fetal Anencephaly. West J Emerg Med. 2016;17(4):460-3. doi:10.5811/westjem.2016.5.30326 - Pubmed