Miliary tuberculosis
Citation, DOI, disclosures and article data
At the time the article was created Jeremy Jones had no recorded disclosures.
View Jeremy Jones's current disclosuresAt the time the article was last revised Henry Knipe had the following disclosures:
- Integral Diagnostics, Shareholder (ongoing)
- Micro-X Ltd, Shareholder (ongoing)
These were assessed during peer review and were determined to not be relevant to the changes that were made.
View Henry Knipe's current disclosures- Miliary TB
- Miliary Koch's infiltration
- Miliary Koch's
Miliary tuberculosis is an uncommon pulmonary manifestation of tuberculosis.
On this page:
Pathology
Miliary tuberculosis represents hematogenous dissemination of uncontrolled tuberculous infection and carries a relatively poor prognosis. It is seen in primary and post-primary tuberculosis and may be associated with tuberculous infection in numerous other tissues and organs.
Radiographic features
Plain radiograph
Miliary deposits appear as 1-3 mm diameter pulmonary nodules that are uniform in size and distribution.
CT
Similar findings to plain radiograph but may more elaborately show extent and distribution.
Treatment and prognosis
If treatment is successful no residual abnormality remains.
History and etymology
John Jacob Manget was the first to use the term miliary tuberculosis in 1700 5. Miliary Koch's infiltration is a historical term, now rarely used (c.2024) to describe miliary tuberculosis 6, and refers to Robert Koch who first isolated Mycobacterium tuberculosis.
Differential diagnosis
The differential diagnosis is of pulmonary miliary opacities.
Quiz questions
References
- 1. Mu X & Wang G. Miliary Tuberculosis. N Engl J Med. 2010;363(11):1059. doi:10.1056/nejmicm1001480
- 2. Jolobe O. Computed Tomography in Miliary Tuberculosis. Arch Dis Child. 2006;91(4):373-4. doi:10.1136/adc.2005.090951
- 3. Reed M, Pagtakhan R, Zylak C, Berg T. Radiologic Features of Miliary Tuberculosis in Children and Adults. J Can Assoc Radiol. 1977;28(3):175-81. PMID 893520
- 4. Furqan M & Butler J. Miliary Pattern on Chest Radiography: TB or Not TB? Mayo Clin Proc. 2010;85(2):108. doi:10.4065/mcp.2009.0523
- 5. Sharma S, Mohan A, Sharma A, Mitra D. Miliary Tuberculosis: New Insights into an Old Disease. Lancet Infect Dis. 2005;5(7):415-30. doi:10.1016/s1473-3099(05)70163-8
- 6. Patel N, Sathvara P, Patel J, Vaghela D. Disseminated Tuberculosis with Paradoxical Miliary Tuberculomas of Brain in a Child with Rickets. J Pediatr Neurosci. 2013;8(3):228. doi:10.4103/1817-1745.123687 - Pubmed
Incoming Links
- Multifocal micronodular pneumocyte hyperplasia
- Disseminated histoplasmosis
- Calcified pulmonary nodules
- Miliary sarcoidosis
- Diffuse pulmonary nodules
- Tuberculosis (pulmonary manifestations)
- Pulmonary Langerhans cell histiocytosis
- Primary pulmonary tuberculosis
- Hepatosplenomegaly
- Pulmonary opacification
- Rich focus
- Tuberculosis
- HIV associated follicular bronchiolitis
- Tuberculosis (summary)
- Miliary opacities (lungs)
- Pulmonary calcification
- Intracranial miliary tuberculomas
- Miliary tuberculosis
- Miliary tuberculosis - CNS and pulmonary
- Paediatric disseminated tuberculosis
- Miliary tuberculosis
- Miliary tuberculosis
- Miliary tuberculosis
- Disseminated tuberculosis
- Extrapulmonary tuberculosis
- Miliary tuberculosis with spondylitis
- Tuberculosis
- Multisystem tuberculosis
- Miliary tuberculosis
- Disseminated tuberculosis with spondylitis (Pott disease) and massive iliopsoas abscesses
- Miliary tuberculosis
- Pulmonary tuberculosis - miliary and endobronchial spread
- Disseminated tuberculosis
- Miliary tuberculosis and haemophagocytic lymphohistiocytosis
- Miliary cerebral tuberculosis
- Miliary tuberculosis
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