Millard Gubler syndrome

Dr Vikas Shah and Dr Amir Rezaee et al.

Millard Gubler syndrome, also known as ventral pontine syndrome, is one of the crossed paralysis syndromes, which are characterised by cranial nerves VI and VII palsies with contralateral body motor or sensory disturbances.

  • ipsilateral facial and contralateral body hemiplegia due to pyramidal tract involvement
  • isotropism and diplopia that is worsened while the patient looks toward the lesion
  • ipsilateral  facial paresis and loss of corneal reflex

Lesions in ventral aspect of the caudal pons involving the fibres of the cranial nerves VI and VII as well as corticospinal tract. 

Aetiology

Causes vary by age

  • young
  • older
    • vascular

Lesions are in ventral aspect of caudal pons with imaging characteristics depend on underlying cause.

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Article Information

rID: 42410
Section: Pathology
Tag: cases
Synonyms or Alternate Spellings:
  • Ventral pontine syndrome

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