Mitral valve disease

Last revised by Daniel J Bell on 6 Mar 2020

Mitral valve disease mostly comprises two main functional abnormalities, which can occur in isolation or in combination:

In addition, other pathologies that affect the mitral valve include:

The mitral valve can also be abnormal in a number of congenital cardiac anomalies.

A normally functioning mitral valve should allow unimpeded blood flow into the left ventricle during diastole and should prevent backflow of blood into the left atrium during systole. 

See also

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