Mitral valve disease (MVD) mostly comprises two main functional abnormalities, which can occur in isolation or in combination:
In addition, other pathologies that affect the mitral valve include:
- mitral valve prolapse
- mitral annular calcification
- mitral valve vegetations from infective endocarditis
A normally functioning mitral valve should allow unimpeded blood flow into the left ventricle during diastole and should prevent backflow of blood into the left atrium during systole.
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